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How AI might be used in nuclear command and control is the subject of much discussion in national security circles. But this debate—important though it has been—obscures many other ways that AI could be used or should not be used across the entire nuclear weapons enterprise. (In this talk, the nuclear weapons enterprise also encompasses nuclear weapons, their delivery systems, the associated command and control and the links of these entities to AI in systems not usually associated with nuclear weapons.) Key attributes of AI and the nuclear weapons enterprise will be reviewed, principles for thinking about AI in the nuclear weapons enterprise discussed, and specific guidelines for assessing the wisdom of AI in any given nuclear application proposed.