This talk will introduce a new set of computational microscopes which use lens-free on-chip imaging to replace traditional lenses with holographic reconstruction algorithms. Basically, 3D images of specimens are reconstructed from their "shadows" providing considerably improved field-of-view (FOV) and depth-of-field, thus enabling large sample volumes to be rapidly imaged, even at nanoscale. These new computational microscopes routinely generate >1–2 billion pixels, where even single viruses can be detected with a FOV that is >100 fold wider than other techniques. At the heart of this leapfrog performance lie self-assembled liquid nano-lenses that are computationally imaged on a chip.
Another major benefit of this technology is that it lends itself to field-portable and cost-effective designs which easily integrate with smartphones to conduct giga-pixel tele-pathology and microscopy even in resource-poor and remote settings where traditional techniques are difficult to implement and sustain, thus opening the door to various telemedicine applications in global health.
This seminar is sponsored by Stanford OSA
Dr. Aydogan Ozcan received his Ph.D. degree at Stanford University Electrical Engineering Department. After a short post-doctoral fellowship at Stanford University, he was appointed as a research faculty at Harvard Medical School, Wellman Center for Photomedicine in 2006. Dr. Ozcan joined UCLA in the summer of 2007 as an Assistant Professor, and was promoted to Associate and Full Professor ranks in 2011 and 2013, respectively. He is currently the Chancellor's Professor at UCLA and an HHMI Professor with the Howard Hughes Medical Institute, leading the Bio- and Nano-Photonics Laboratory at UCLA Electrical Engineering and Bioengineering Departments, and is also the Associate Director of the California NanoSystems Institute (CNSI) at UCLA.